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. Author manuscript; available in PMC: 2019 Aug 18.
Published in final edited form as: Lab Invest. 2019 Feb 18;99(6):807–818. doi: 10.1038/s41374-019-0204-2

Figure 6. Tcf7l2 levels control the expression of Lef1, Tcf7, Cyclin D2, and Bmp4.

Figure 6.

The mRNA levels of HL-1 CMs transfected with wild type long-form Tcf7l2 (Ade WT), Tcf7l2 shRNA (sh RNA), and control vector (pGPIZ) are quantified and compared with non-transfected group (Control) by real time RT-PCR 72 hours after transfection. Tcf7l2 shRNA significantly increases transcript levels of Lef1, Tcf7, Cyclin D2, and Bmp4. The mRNA levels of Bmp4 and Cyclin D2 are downregulated by Tcf7l2 overexpression. Data are presented as mean±SD from 4 independent experiments.