Table 3.
Clinical condition of patients with mesenteric malperfusion syndrome divided into three groups based on the outcome of endovascular reperfusion
| Death from organ failure (n=20) | Survival* (n=51) |
Death from aortic rupture (n=11) | p-value | |
|---|---|---|---|---|
| Age on admission (years) | 58 (47-73) | 57 (51-65) | 63 (58-69) | 0.65 |
| Gender (female) | 8 (40) | 12 (24) | 2 (18) | 0.27 |
| CAD | 5 (28) | 11 (22) | 1 (10) | 0.11 |
| History of MI | 4 (21) | 4 (7.8) | 1 (10) | 0.20 |
| Previous cardiac surgery | 3 (15) | 9 (18) | 1 (9.1) | 1 |
| Hypertension | 16 (84) | 44 (86) | 5 (50) | 1 |
| COPD | 1 (5.0) | 5 (9.8) | 1 (9.1) | 0.67 |
| Diabetes | 0 (0) | 2 (3.9) | 0 (0) | 1 |
| Creatinine on admission (mg/dL) | 1.4 (1.1, 2.5) | 1.4 (1.0, 2.6) | 1.3 (1.1, 1.4) | 0.88 |
| GFR on admission (mL/min/1.73 m2) | 67 (42-93) | 69 (47-96) | 62 (48-92) | 0.98 |
| Chronic kidney disease | 3 (16) | 5 (9.8) | 0 (0) | 0.67 |
| History of CVA | 0 (0) | 3 (5.9) | 0 (0) | 0.55 |
| PVOD | 2 (10) | 7 (14) | 0 (0) | 1 |
| Cardiogenic shock | 3 (20) | 0 (0) | 0 (0) | 0.01 |
| Acute stroke | 8 (40) | 2 (3.9) | 0 (0) | < 0.001 |
| Acute paralysis | 2 (10) | 4 (7.8) | 0 (0) | 1 |
| Acute MI | 0 (0) | 0 (0) | 1 (9.1) | 1 |
| Pre-operative CPR | 0 (0) | 1 (2.0) | 0 (0) | 1 |
| AKI | 16 (80) | 38 (75) | 8 (73) | 0.76 |
| Requiring new dialysis pre-operatively | 1 (5.0) | 4 (7.8) | 0 (0) | 1.0 |
| Renal malperfusion | 15 (75) | 33 (65) | 7 (64) | 0.65 |
| Lower extremity malperfusion | 11 (55) | 36 (71) | 6 (55) | 0.33 |
| Bowel necrosis at laparotomy | 5 (25) | 4 (7.8) | 0 (0) | 0.12 |
| Max serum lactate before IR (mmol/L) | 3.0 (2.2, 6.8) | 1.6 (1.2, 3.2) | 2.2 (1.6, 2.7) | 0.02 |
| Max serum lactate before IR ≥ 6 mmol/L | 5 (31) | 2 (5) | 0 (0) | 0.02 |
Survival: means patients survived to open aortic repair or discharge without open repair. P value indicates the difference between the groups of death from organ failure and survival to open aortic repair or hospital discharge.
AKI = acute kidney injury; CAD = coronary artery disease; COPD = chronic obstructive pulmonary disease; CPR = cardiopulmonary resuscitation; CVA = cerebrovascular accident; GFR = glomerular filtration rate as estimated using the Cockcroft-Gault formula; IR = endovascular procedure by interventional radiology; MI = myocardial infarction; MPS = malperfusion syndrome; NYHA = New York Heart Association; PVOD = peripheral vascular occlusive disease.