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. Author manuscript; available in PMC: 2020 Aug 1.
Published in final edited form as: Clin Gastroenterol Hepatol. 2018 Dec 14;17(9):1886–1893.e5. doi: 10.1016/j.cgh.2018.12.005

Table 1:

Sensitivity analysis evaluating the HES algorithm when 1,358 unverified HCC cases were excluded.

Patient-level sensitivity
corresponding to 10% screening-
level false positive rate
3,456 HCC cases; 33,627 cirrhosis controls
6 months 12 months 24 months Ever
HES algorithm 52.30 (95% CI:50.32-53.17) 52.81 (95% CI:50.98-53.49) 53.88 (95% CI:52.51-54.49) 54.83 (95% CI:53.26-55.64)
AFP only 48.52 (95% CI:46.28-49.40) 48.54 (95% CI:46.63-49.04) 49.34 (95% CI:47.17-50.19) 50.46 (95% CI:48.46-51.39)
Bootstrap p-values: <0.0005 <0.0005 <0.0005 <0.0005