#	Searches	Results
1	exp Carcinoma, Renal Cell/sc	5615
2	(((“renal cell” or “collecting duct”) adj3 cancer*) or ((renal or kidney or hypernephroid or “hyper-nephroid” or “Collecting Duct*” or nephroid*) adj3 (cancer* or neoplasm* or tumor* or tumour* or carcinoma* or adenocarcinoma* or hypernephroma or “hyper-nephroma*” or pyelocarcinoma or “pyelo-carcinoma*”)) or “grawitz tumor*” or “grawitz tumour*” or hypernephroma*).ti,ab,hw,kw.	202004
3	exp Neoplasm Metastasis/	688965
4	((secondary adj3 (cancer* or neoplasm* or tumor* or tumour* or carcinoma* or adenocarcinoma* or hypernephroma or “hyper-nephroma*” or pyelocarcinoma or “pyelo-carcinoma*” or “grawitz tumor*” or “grawitz tumour*” or hypernephroma*)) or metastas* or metastatic* or micrometastas* or micrometastatic*).ti,ab,hw,kw.	1243561
5	1 or (2 and (3 or 4))	65767
6	Cytoreduction Surgical Procedures/	12762
7	((cytoreduc* or debulk* or radical*) adj3 (nephrectom* or surg* or resect* or operat*)).ti,ab,hw,kw.	104554
8	6 or 7	104554
9	5 and 8	7262
10	exp survival/	911936
11	exp death/	732815
12	exp mortality/	1233613
13	mortality.fs.	561511
14	exp survival analysis/	305801
15	(surviv* or death* or mortalit* or fatalit*).mp.	5568550
16	or/10–15	5896880
17	9 and 16	3998
18	limit 17 to english language [Limit not valid in CDSR; records were retained]	3472
19	limit 18 to yr=“2004 -Current”	2852
20	limit 19 to (letter or conference abstract or editorial or erratum or note or addresses or autobiography or bibliography or biography or blogs or comment or dictionary or directory or interactive tutorial or interview or lectures or legal cases or legislation or news or newspaper article or overall or patient education handout or periodical index or portraits or published erratum or video-audio media or webcasts) [Limit not valid in Embase,CCTR,CDSR,Ovid MEDLINE(R),Ovid MEDLINE(R) Daily Update,Ovid MEDLINE(R) In-Process,Ovid MEDLINE(R) Publisher; records were retained]	871
21	19 not 20	1981
22	(exp animals/or exp nonhuman/) not exp humans/	9466935
23	((alpaca or alpacas or amphibian or amphibians or animal or animals or antelope or armadillo or armadillos or avian or baboon or baboons or beagle or beagles or bee or bees or bird or birds or bison or bovine or buffalo or buffaloes or buffalos or “c elegans” or “Caenorhabditis elegans” or camel or camels or canine or canines or carp or cats or cattle or chick or chicken or chickens or chicks or chimp or chimpanze or chimpanzees or chimps or cow or cows or “D melanogaster” or “dairy calf” or “dairy calves” or deer or dog or dogs or donkey or donkeys or drosophila or “Drosophila melanogaster” or duck or duckling or ducklings or ducks or equid or equids or equine or equines or feline or felines or ferret or ferrets or finch or finches or fish or flatworm or flatworms or fox or foxes or frog or frogs or “fruit flies” or “fruit fly” or “G mellonella” or “Galleria mellonella” or geese or gerbil or gerbils or goat or goats or goose or gorilla or gorillas or hamster or hamsters or hare or hares or heifer or heifers or horse or horses or insect or insects or jellyfish or kangaroo or kangaroos or kitten or kittens or lagomorph or lagomorphs or lamb or lambs or llama or llamas or macaque or macaques or macaw or macaws or marmoset or marmosets or mice or minipig or minipigs or mink or minks or monkey or monkeys or mouse or mule or mules or nematode or nematodes or octopus or octopuses or orangutan or “orangutan” or orangutans or “orang-utans” or oxen or parrot or parrots or pig or pigeon or pigeons or piglet or piglets or pigs or porcine or primate or primates or quail or rabbit or rabbits or rat or rats or reptile or reptiles or rodent or rodents or ruminant or ruminants or salmon or sheep or shrimp or slug or slugs or swine or tamarin or tamarins or toad or toads or trout or urchin or urchins or vole or voles or waxworm or waxworms or worm or worms or xenopus or “zebra fish” or zebrafish) not (human or humans or patient or patients)).ti,ab,hw,kw.	8138953
24	21 not (22 or 23)	1977
25	(case adj3 report).mp,pt.	2281039
26	24 not 25	1798
27	remove duplicates from 26	1051

Database(s): Embase 1988 to 2018 Week 01, EBM Reviews - Cochrane Central Register of Controlled Trials November 2017, EBM Reviews - Cochrane Database of Systematic Reviews 2005 to December 28, 2017, Ovid MEDLINE(R) Epub Ahead of Print, In-Process & Other Non-Indexed Citations, Ovid MEDLINE(R) Daily and Ovid MEDLINE(R) 1946 to Present.