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The protection efficacy of DNA vaccine in mice infected with 108 CFU of A. baumannii and receiving 100 µg/ µl the pBudCE4.1-ompA, the pBudCE4 and phosphate buffer saline (PBS)
| Group | IM Injection |
Challenge
|
% Protection | |
|---|---|---|---|---|
| Live | Dead | |||
| PBS (N= 10) | 100µl x 4 | - | 10 | (0%) |
| pBudCE4.1 (N= 10) | 0.25µg/ µl x 4=(100 µg/ µl) | - | 10 | (0%) |
| pBudCE4.1-ompA (N= 10) | 0.25µg/ µl x 4=(100 µg/ µl) | 6 | 4 | (60%) |
