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. 2019 Jun 14;5:21. doi: 10.1038/s41540-019-0097-0

Table 1.

Combinatorial perturbation conditions

Expression condition Description
WT Control
TGF-β TGF-β treatment
dZEB CRISPR-mediated ZEB1 knockout
TGF-β+dZEB TGF-β treatment and ZEB1 knockout
DMSO Control for doxycycline-induction of ZEB1 and SB431542
DOX Doxycycline-induction of ZEB1
SB TGF-β inhibition by TGF-β receptor kinase inhibitor SB431542
DOX+SB ZEB1 over-expression and TGF-β inhibition