Table 1.
Outcome of subsequent open surgery stratified by histological parameters on core needle biopsy (CNB, 14G) and vacuum-assisted biopsy (VAB, 7–11G)
| Histological and biopsy characteristics | CNB; n = 56 | VAB; n = 151 | |||
|---|---|---|---|---|---|
| Underestimation | |||||
| No | Yes | No | Yes | ||
| Method of biopsy (CNB vs VAB) | 24 (42.86%) | 32 (57.14%) | 101 (66.89%) | 50 (33.11%) | |
| ADH | |||||
| Pure | 18 (40.91%) | 26 (59.09%) | 39 (62.90%) | 23 (37.10%) | |
| Not pure | 6 (50.00%) | 6 (50.00%) | 62 (69.66%) | 27 (30.34%) | |
| FEA | |||||
| Absent | 17 (40.48%) | 25 (59.52%) | 42 (68.85%) | 19 (31.15%) | |
| Present | 7 (50.00%) | 7 (50.00%) | 59 (65.56%) | 31 (34.44%) | |
| RS | |||||
| Absent | 24 (42.86%) | 32 (57.14%) | 94 (65.73%) | 49 (34.27%) | |
| Present | – | – | 7 (87.50%) | 1 (12.50%) | |
| LN | |||||
| Absent | 24 (42.86%) | 32 (57.14%) | 90 (67.16%) | 44 (32.84%) | |
| Present | – | – | 11 (64.71%) | 6 (35.29%) | |
| Calcifications | |||||
| Absent | 19 (45.24%) | 23 (54.76%) | 19 (55.88) | 15 (44.12%) | |
| Present | 5 (35.71%) | 9 (64.29%) | 82 (70.09%) | 35 (29.91%) | |
| Diameter | |||||
| 1.1–2 mm | 9 (40.91%) | 13 (59.09%) | 49 (69.01%) | 22 (30.99%) | |
| Up to 1 mm | 15 (44.12%) | 19 (55.88%) | 52 (65.00%) | 28 (35%) | |
| Multifocality | |||||
| Multifocal | 4 (36.36%) | 7 (63.64%) | 34 (55.74%) | 27 (44.26%) | |
| Unifocal | 20 (44.44%) | 25 (55.56%) | 67 (74.44%) | 23 (24.56%) | |
| Papilloma | |||||
| Absent | 21 (42.86%) | 28 (57.14%) | 93 (65.49%) | 49 (34.51%) | |
| Present | 3 (42.86%) | 4 (57.14%) | 8 (88.89%) | 1 (11.11%) | |
Underestimation is “yes”, when DCIS or invasive cancer was found on subsequent open surgery
ADH atypical ductal hyperplasia, FEA flat epithelial atypia, RS radial scar, LN lobular neoplasia, classical type. Pure ADH: absence of FEA, RS, LN or papilloma in the biopsy