Table 4.
Logistic regression models for underestimation in vacuum-assisted biopsies (VAB) (N = 151)
| Effect | Univariate | Multivariate | ||||||
|---|---|---|---|---|---|---|---|---|
| Odds ratio | 95% Wald confidence limits | p value | Odds ratio | 95% Wald confidence limits | p value | |||
| ADH | 1.35 | 0.68 | 2.69 | 0.386 | 1.22 | 0.40 | 3.67 | 0.730 |
| FEA | 1.16 | 0.58 | 2.33 | 0.673 | 1.35 | 0.45 | 4.05 | 0.592 |
| RS | 0.27 | 0.03 | 2.29 | 0.232 | 0.29 | 0.03 | 2.97 | 0.295 |
| LN | 1.12 | 0.39 | 3.21 | 0.839 | 0.84 | 0.25 | 2.83 | 0.783 |
| Extension | 0.83 | 0.42 | 1.65 | 0.601 | 0.85 | 0.41 | 1.77 | 0.662 |
| Multifocality | 2.31 | 1.16 | 4.62 | 0.018* | 2.66 | 1.22 | 5.80 | 0.014* |
| Calcification | 0.54 | 0.25 | 1.18 | 0.124 | 0.35 | 0.14 | 0.88 | 0.025* |
| Papillomas | 0.24 | 0.03 | 1.95 | 0.181 | 0.33 | 0.03 | 3.31 | 0.346 |
Univariate and multivariate logistic regression analyses of disease underestimation by vacuum-assisted biopsy. Associated B3 lesions or the diameter of the lesion had no significant effect, but multifocality and associated calcification significantly affected the upgrade rates for vacuum-assisted biopsy samples (7–11G)
ADH atypical ductal hyperplasia, FEA flat epithelial atypia, RS radial scar, LN lobular neoplasia, classical type
*Statistically significant