Table 2:

Major manifestations and causes of disease

Disease	Major manifestations (Mg deficiency)	Causes (Mg deficiency)
Cerebral vasospasm	Acute focal vasospasm Contraction reaction Platelet aggregation	Insufficient magnesium intake Excessive loss of digestive tract (Deleterious effect of common medications on magnesium absorption) ( 60 ) Excessive loss of kidney (61) Hyperthyroidism
Stroke	Inflammatory response Oxidative response
AD	Reduced synaptic plasticity
PD	α-synuclein aggregation Release of neurotransmitter
Migraine	Hyper aggregated of platelets Cortical spreading depression