Table 3:

Allele and genotype distribution of various SNPs of ERAP1, 2 in preeclampsia cases and healthy controls

dbSNP	Alleles/Genotypes	Case (n=148) N (%)	Control (n=133) N (%)	P value	OR (95% CI)
rs28096	A	110 (37.4)	105 (39.5)	0.61	0.91 (0.65–1.28)
	G	184 (62.16)	161 (60.5)	0.61	1.09 (0.77–1.53)
	AA	19 (12.9)	20 (15.0)	0.61	0.83 (0.42–1.65)
	AG	72 (49.0)	65 (48.9)	0.98	1.00 (0.62–1.60)
	GG	56 (38.1)	48 (36.1)	0.72	1.08 (0.67–1.77)
HWE			0.798
rs30187	T	129 (43.6)	102 (38.9)	0.26	1.21 (0.86–1.69)
	C	167 (56.4)	160 (61.1)	0.26	0.82 (0.58–1.15)
	TT	28 (18.9)	18 (13.7)	0.24	1.46 (0.76–2.79)
	TC	73 (49.3)	66 (50.4)	0.86	0.95 (0.59–1.53)
	CC	47 (31.8)	47 (35.9)	0.46	0.83 (0.50–1.36)
HWE			0.498
rs26653	C	122 (41.5)	112 (42.1)	0.88	0.97 (0.69–1.36)
	G	172 (58.5)	154 (57.9)	0.88	1.02 (0.73–1.43)
	CC	27 (18.4)	25 (18.8)	0.92	0.97 (0.53–1.77)
	CG	68 (46.3)	62 (46.6)	0.95	0.98 (0.61–1.57)
	GG	52 (35.4)	46 (34.6)	0.89	1.03 (0.63–1.69)
HWE			0.618
rs3734016	A	293 (99.0)	266 (100)	0.099	-
	G	3 (1)	0 (0)	0.099	-
	AA	145 (98.0)	133 (100)	0.099	-
	AG	3 (2)	0 (0)	0.099	-
	GG	0 (.0)	0 (0)	-	-
HWE			1.00
rs34750	C	174 (59.18)	155 (58.27)	0.82	1.03 (0.74–1.45)
	G	120 (40.82)	111 (41.73)	0.82	0.96 (0.68–1.34)
	CC	54 (36.73)	47 (35.34)	0.80	1.06 (0.65–1.73)
	CG	66 (44.90)	61 (45.86)	0.87	0.96 (0.60–1.54)
	GG	27 (18.37)	25 (18.80)	0.21	0.97 (0.53–1.77)
HWE			0.51
rs2549782	T	121 (40.88)	107 (40.23)	0.87	1.02 (0.73–1.43)
	G	175 (59.12)	159 (59.77)	0.87	0.97 (0.69–1.36)
	TT	51 (34.5)	43 (32.3)	0.70	1.10 (0.66–1.80)
	TG	73 (49.3)	73 (54.9)	0.35	0.80 (0.50–1.27)
	GG	24 (16.2)	17 (12.8)	0.41	1.32 (0.67–2.58)
HWE			0.10
rs17408150	A	25 (8.4)	34 (12.8)	0.094	0.62 (0.36–1.08)
	T	271 (91.6)	232 (87.2)	0.094	1.58 (0.92–2.74)
	AA	0 (0)	3 (2.3)	0.066	-
	AT	25 (16.9)	28(21.1)	0.37	0.76 (0.41–1.38)
	TT	123 (83.1)	102(76.7)	0.17	1.49 (0.83–2.69)
HWE			0.52

OR, odds ratio; CI, confidence interval; - means Not Calculated