Table 4:
Overall haplotype associations of the single-nucleotide polymorphisms according to Haploview
| Block 1 Haplotypes | Frequencies | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Row | rs28096 | rs30187 | rs26653 | rs3734016 | rs34750 | rs2549782 | rs17408150 | Hap.freq (Case) | Hap.freq (Control) | OR* (95% CI) | P value |
| 1 | A | C | C | A | G | T | T | 31 (10) | 26 (10) | 1.05 (0.60–1.81) | 0.85 |
| 2 | A | C | G | A | C | G | T | 29 (10) | 7 (3) | 3.65 (1.63–8.20) | 0.00082 |
| 3 | A | C | G | A | C | T | T | 43 (15) | 61 (23) | 0.55 (0.36–0.86) | 0.00791 |
| 4 | A | T | C | A | G | G | A | 1 (0.5) | 1 (0.4) | - | - |
| 5 | G | C | G | A | C | G | T | 41 (14) | 39 (15) | 0.91 (0.56–1.46) | 0.70 |
| 6 | G | C | G | A | C | T | T | 12 (4) | 17 (6) | 0.63 (0.30–1.33) | 0.22 |
| 7 | G | T | C | A | G | G | A | 10 (3.6) | 20 (8) | 0.41 (0.19–0.89) | 0.02 |
| 8 | G | T | C | A | G | G | T | 18 (6.2) | 14 (5.5) | 1.12 (0.55–2.30) | 0.74 |
| 9 | G | T | C | A | G | T | T | 56 (19.3) | 40 (15) | 1.30 (0.83–2.03) | 0.24 |
| 10 | G | T | G | A | C | G | A | 12 (4.4) | 11 (4) | 1.02 (0.44–2.32) | 0.96 |
| 11 | G | T | G | A | C | G | T | 2 (0.8) | 2 (1.1) | - | - |
| 12 | G | T | G | A | C | T | T | 24 (8.5) | 9 (4) | 2.40 (1.12–5.15) | 0.02 |
*
OR, odds ratio; CI, 95% confidence interval for difference between Haplotype frequency of case-control; -means Not Calculated