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. 2019 Jun 15;19:587. doi: 10.1186/s12885-019-5786-y

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — To show the genomic changes, 4 sites (upper) in Figs. 1 and 2 sites (bottom) in Fig. 2 were chosen and zoomed up in representative cells (HLF, 520d-5p 7D, and hMSC). The changes in genomic fragments were less than those of chromosomes. The chosen sites are shown as ★ in Figs. 1 and 2