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. 2019 Jun 14;38:259. doi: 10.1186/s13046-019-1262-4

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 6 — High PTEN levels correlate with USP13 overexpression in a subset of human bladder cancer tissue specimens. a. Representative images demonstrating PTEN and USP13 immunohistochemistry (IHC) staining of human bladder cancer tissue specimens from 30 bladder cancer patients. b. Quantification of PTEN or USP13 staining in BC tissue specimens. Staining intensity of PTEN or USP13 was scored as 0 to3 (0: no staining, 1: weak staining, 2: medium staining, and 3: strong staining. 0 and 1 were classified as low-expression, whereas 2 and 3 were defined as high-expression. High PTEN expression was correlated with high USP13 expression (p < 0.05, Fisher’s exact test)