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. 2019 Jun 11;4(3):e001410. doi: 10.1136/bmjgh-2019-001410

Table 1.

Paired government procurement prices, originator and biosimilar insulins, 1000 IU in US dollars

Survey Human insulin, strength, presentation Originator(s) Biosimilar(s) Difference biosimilar to originator
Pakistan Regular, isophane and mixed 30/70, 100 IU/mL vial $2.38 N $2.00 G 16% ↓
Kazan, Russia Regular 100 IU/mL vial $6.07 N $6.65 P 10% ↑
Shaanxi, China Mixed 30/70 40 IU/mL vial $21.26 N $18.90 D 11% ↓
Isophane 100 IU/mL cartridge $28.35 N $24.23 U; $25.21 D 11%–14% ↓
Mixed 30/70 100 IU/mL cartridge $28.35 N $25.21 U; $25.21 D 11% ↓
Mixed 50/50 100 IU/mL cartridge $28.35 N $25.05 U; $26.96 D 5%–12%↓
Hubei, China Regular 40 IU/mL vial $20.70 N $17.71 D 14% ↓
Isophane 40 IU/mL vial $20.76 N $17.71 D 14% ↓
Mixed 30/70 40 IU/mL vial $21.39 N $17.94 D 16% ↓
Regular 100 IU/mL cartridge $26.51 L; $26.53 N $23.18 Li; $23.62 D; $27.41 Bt 3% ↑–13% ↓
Isophane 100 IU/mL cartridge $26.20 L; $27.47 N $23.35 Li; $24.24 D; $28.11 Bt 7% ↑–15% ↓
Mixed 30/70 100 IU/mL cartridge $26.44 L; $26.66 N $22.56 Li; $23.80 D; $27.84 Bt 5% ↑–15% ↓
Mixed 50/50 100 IU/mL cartridge $27.78 N $22.09 Li; $26.23 D 6%–20% ↓

Originator companies: L, Lilly; N, Novo Nordisk.

Biosimilar companies: Bt, Bioton; D, Tonghua Dongbao; G, Getz; Li, Lianbang; P, Pharmstandard; U, United.