Table 1.
Survey | Human insulin, strength, presentation | Originator(s) | Biosimilar(s) | Difference biosimilar to originator |
Pakistan | Regular, isophane and mixed 30/70, 100 IU/mL vial | $2.38 N | $2.00 G | 16% ↓ |
Kazan, Russia | Regular 100 IU/mL vial | $6.07 N | $6.65 P | 10% ↑ |
Shaanxi, China | Mixed 30/70 40 IU/mL vial | $21.26 N | $18.90 D | 11% ↓ |
Isophane 100 IU/mL cartridge | $28.35 N | $24.23 U; $25.21 D | 11%–14% ↓ | |
Mixed 30/70 100 IU/mL cartridge | $28.35 N | $25.21 U; $25.21 D | 11% ↓ | |
Mixed 50/50 100 IU/mL cartridge | $28.35 N | $25.05 U; $26.96 D | 5%–12%↓ | |
Hubei, China | Regular 40 IU/mL vial | $20.70 N | $17.71 D | 14% ↓ |
Isophane 40 IU/mL vial | $20.76 N | $17.71 D | 14% ↓ | |
Mixed 30/70 40 IU/mL vial | $21.39 N | $17.94 D | 16% ↓ | |
Regular 100 IU/mL cartridge | $26.51 L; $26.53 N | $23.18 Li; $23.62 D; $27.41 Bt | 3% ↑–13% ↓ | |
Isophane 100 IU/mL cartridge | $26.20 L; $27.47 N | $23.35 Li; $24.24 D; $28.11 Bt | 7% ↑–15% ↓ | |
Mixed 30/70 100 IU/mL cartridge | $26.44 L; $26.66 N | $22.56 Li; $23.80 D; $27.84 Bt | 5% ↑–15% ↓ | |
Mixed 50/50 100 IU/mL cartridge | $27.78 N | $22.09 Li; $26.23 D | 6%–20% ↓ |
Originator companies: L, Lilly; N, Novo Nordisk.
Biosimilar companies: Bt, Bioton; D, Tonghua Dongbao; G, Getz; Li, Lianbang; P, Pharmstandard; U, United.