Table 1.

Antigens reported to cause HP

Antigen Subtype	Examples	Exposure Sources	Resultant Disease
Bacteria	Saccharopolyspora rectivirgula, Thermoactinomyces vulgaris, absidia corymbifera	Moldy hay, grain, silage	Farmer’s Lung
Fungi, yeast	Aspergillus sp.	Moldy hay, grain	Farmer’s Lung
		Moldy compost and mushrooms	Mushrooms Worker’s Lung
	Trichosporon cutaneum	Contaminated homes	Summer-Type HP
	Penicillium sp. Penicillium	Moldy cork	Suberosis
		Moldy cheese or cheese casings	Cheese Washer’s Lung
		Dry sausage dust in salami factories	Chacinero’s Lung
	Alternaria sp.	Contaminated oak, cedar and mahogany dust. Pine and spruce pulp.	Woodworker’s Lung
Mycobacteria	Mycobacterium avium-intracellulare	Mold on ceiling or walls, tub water	Hot Tub Lung
		Mist from pool water, sprays and fountains	Swimming Pool Lung
Animal Proteins	Proteins in avian droppings and serum and on feathers	Parakeets, pigeons, parrots, cockatiels, ducks, chickens, turkeys	Pigeon Breeder’s Lung Bird Fancier’s Lung
	Animal fur dust	Animal pelts	Furrier’s Lung
	Rats, gerbils	Urine, serum, pelt proteins	Laboratory Worker’s Lung
	Avian proteins	Feather beds, pillows, duvets	Feather Duvet Lung
	Silkworm proteins	Dust from silkworm larvae and cocoons	Silk Production HP
Chemicals	Diisocyanates, toluene, trimelletic anhydride.	Polyurethane foams, spray paints, dyes, glues, varnishes, lacquer	Chemical Worker’s Lung
	Pyrethrum	Insecticide	Pyrethrum pneumonitis