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. Author manuscript; available in PMC: 2019 Jul 1.
Published in final edited form as: Hypertens Res. 2019 Jan 21;42(7):960–969. doi: 10.1038/s41440-019-0212-z

Fig. 3.

Fig. 3

Metformin inhibits oxidative stress. a NADPH oxidase activity and b immunofluorescence for 8-Oxo-2′-deoxyguanosine (8-OHDG) show an increase in oxidative stress in the MRA of C57/Bl6 mice after Ang II infusion (400 ng/kg/min), which was significantly reduced with metformin treatment (300 mg.kg−1 body weight per day).*p < 0.05 vs Sham + Ang II. #p < 0.05 vs Sham