Table 1:

Elements required for unambiguous reporting of uncertainty scenarios and their dosimetric effects.

Element to Report	Example(s)
For Reporting Uncertainty Scenarios
Type of uncertainty	Lateral translations Rotations (pitch around lateral axis) Hounsfield Unit uncertainty
Magnitude of uncertainty value	+ 1 cm
Relative likelihood of uncertainty value	Represented as a probability distribution
Correlation between uncertainties	Covariance matrix for a multivariate normal distribution
Number of sample scenarios	1,000 random samples
Determination of dose for each scenario	Dose recalculated Dose resampled from the nominal dose distribution
For Reporting Dosimetric Effects of Uncertainty Scenarios
Form of the dosimetric representation	3D dose distribution DVH Equivalent Uniform Dose
Dosimetric representation descriptor	Mean Standard deviation Minimum Maximum nth percentile
Determination of the dosimetric descriptor	The “minimum DVH” as the DVH derived from the minimum dose per voxel of the 3D dose distributions under the uncertainty scenarios The “minimum DVH” as the dose-bin- wise minimum value of the many DVH’s under the uncertainty scenarios