Table 1.
Patient demographics and clinical characteristics
| Characteristic | Overall N = 1030 |
Current ECOG performance status | |||
|---|---|---|---|---|---|
| 0 n = 200 |
1 n = 448 |
2 n = 282 |
3 or 4 n = 100 |
||
| Age, mean (SD) years | n = 1028 | n = 200 | n = 447 | n = 281 | n = 100 |
| 64.5 (10.1) | 59.2 (9.2) | 63.5 (9.8) | 67.7 (8.9) | 70.5 (10.2) | |
| Male, n (%) | n = 1030 | n = 200 | n = 448 | n = 282 | n = 100 |
| 679 (65.9) | 123 (61.5) | 308 (68.8) | 182 (64.5) | 66 (66.0) | |
| Smoking status, n (%) | n = 1010 | n = 197 | n = 439 | n = 277 | n = 97 |
| Never-smoker | 223 (22.1) | 69 (35.0) | 88 (20.0) | 47 (17.0) | 19 (19.6) |
| Current/ex-smoker | 787 (77.9) | 128 (65.0) | 351 (80.0) | 230 (83.0) | 78 (80.4) |
| Disease duration, mean (SD) weeks | n = 1015 | n = 200 | n = 436 | n = 280 | n = 99 |
| 35.9 (44.9) | 29.8 (45.0) | 33.7 (38.5) | 43.6 (51.7) | 35.9 (47.9) | |
| Histological type, n (%) | n = 1030 | n = 200 | n = 448 | n = 282 | n = 100 |
| Non-squamous | 724 (70.3) | 148 (74.0) | 313 (69.9) | 190 (67.4) | 73 (73.0) |
| Squamous | 306 (29.7) | 52 (26.0) | 135 (30.1) | 92 (32.6) | 27 (27.0) |
| Current NSCLC stage, n (%) | n = 1030 | n = 200 | n = 448 | n = 282 | n = 100 |
| Stage IIIb | 119 (11.6) | 24 (12.0) | 53 (11.8) | 29 (10.3) | 13 (13.0) |
| Stage IV | 911 (88.4) | 176 (88.0) | 395 (88.2) | 253 (89.7) | 87 (87.0) |
| Line of therapy, n (%) | n = 1022 | n = 199 | n = 441 | n = 282 | n = 100 |
| First | 720 (70.5) | 173 (86.9) | 315 (71.4) | 160 (56.7) | 72 (72.0) |
| Second or later | 302 (29.5) | 26 (13.1) | 126 (28.6) | 122 (43.3) | 28 (28.0) |
ECOG Eastern Cooperative Oncology Group, NSCLC non-small cell lung cancer, SD standard deviation