Figure 6. Delayed Recall is associated with cortical atrophy in FPN and DMN systems, while Retention is not associated with cortical atrophy but with hippocampal volume loss.
Exploratory whole cortical surface general linear models of Delayed Recall and Retention show different patterns of related atrophy, with (A) regions of the FPN and DMN associated with Delayed Recall performance and (B) anterior MTL associated with Retention, at a significance threshold set at p < 0.001. Follow-up hierarchical linear regression revealed that Delayed Recall and Retention were associated only with hippocampal volume (not shown on these cortical surface maps).