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. 2019 May 8;30(10):700–706. doi: 10.1097/WNR.0000000000001262

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Copyright © 2019 The Author(s). Published by Wolters Kluwer Health, Inc.

This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal. http://creativecommons.org/licenses/by-nc-nd/4.0/

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Fig. 2 — Differences in the functional connectivity (FC) levels from the left hippocampus among groups. (a) Statistical comparison of FC toward the left putamen, left thalamus, left precuneus, and right precentral gyrus among the three groups. FCs in the drug-resistant (DR) group largely decreased or remained unchanged, while they exhibited compensatory enhancement in drug-sensitive (DS) patients. (b) Regions with differential FCs from the right hippocampus among three groups; (c) FCs between the left hippocampus and the right precentral gyrus, left putamen, and left precuneus were enhanced in the DS group versus normal control (NC); (d) FCs between the left hippocampus and the left thalamus/left putamen demonstrated significant attenuation in the DR versus NC groups. The FC level between the left hippocampus and the left precuneus decreased slightly in the DR group versus the NC group. (e) FCs between the left hippocampus and left thalamus/left putamen/left precuneus were attenuated in the DR group compared to the DS group. *P<0.05 versus the NC; **P<0.01 versus the NC.