Figure 4.

Substitution to serine at position 282^7.55 is specific to strepsirrhines. Maximum-likelihood tree was reconstructed based on the amino acid sequences of TAS2R16 in primates. The amino acid residue at position 282^7.55 in each species is indicated at each tip of the tree (diamonds indicate serine, circles indicate leucine, triangles indicate alanine and methionine). Bootstrap values are expressed at the nodes of the tree. The amino acid residue at position 282^7.55 and the corresponding codon of primates are shown next to the species name. (Online version in colour.)