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. 2019 May 20;203(1):58–75. doi: 10.4049/jimmunol.1900043

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Copyright © 2019 by The American Association of Immunologists, Inc.

This article is distributed under The American Association of Immunologists, Inc., Reuse Terms and Conditions for Author Choice articles.

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FIGURE 9. — Kidney parenchymal cell expression of genes linked to nephrotic syndrome and injury associated genes are altered during disease and normalized by anti-CD40 treatment. The median expression levels of nephrotic syndrome linked genes (A and B), injury associated genes (C and D) and collagen genes (E) are shown to compare young prediseased mice with the different treatment groups. The genes for each group are listed in Supplemental Table I. Injury associated genes and nephrotic linked genes are divided into two groups: those that are increased during disease and those that are decreased with disease. Young (n = 5), vehicle (n = 4), and anti-CD40 (n = 12) and prednisolone (n = 9). *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001 by one-way ANOVA.