Table 4.

Synthetic Protocol A (For more details see Supporting Information).

Procedure	Reagents	Volume/Time
H-Phosphonate/H-Phosphinate Condensation Step
Deblocking	3% DCA in DCM	Flow through the column 6 mL/2 min
Condensation	0.1M monomer in ACN/Py (1:1)	120 µL/10min
	0.3M DMOCP in ACN/Py (95:5)
Oxidation	Ox-A, Ox-B, Ox-D	220 µL/30 min
Methyl-ester cleavage *	PhSH/Et3N/DMF(1:1.4:2)	300 µL/4 h
Cleavage from solid support	Gaseous ammonia at 0.7 MPa	Gas chamber/16 h

* Applicable only in case of Ox-A and Ox-B mixtures containing methanol.