ACS
|
Acetyl-CoA Synthase. |
AGC
|
aspartate-glutamate carrier (see T4 in Appendix A) |
AKG
|
α-ketoglutarate or 2-oxoglutarate |
ANT
|
ADP/ATP exchanger. |
ARGASE
|
arginase |
ASS1_ASL_FH
|
argininosuccinate synthase + argininosuccinate lyase + fumarate hydratase |
ASYNT
|
ATP Synthase. |
ASPUP
|
Uptake of aspartate. |
ATPASE
|
ATP usage. |
BM
|
0.18 SERc + 0.11 Palmitate_c + 0.04 XTPc + 0.19 GLNc + 0.17 GLUTc + 0.7 ASPc + 0.05 ARGc + 0.12 PYRc + 4 ATPc => 1 Biomass + 4 ADPc + 4 Pic. |
CL (ACL)
|
(ATP) Citrate Lyase. |
CPS1_OTC
|
carbamoyl phosphate synthase 1 + Ornithine transcarbamylase |
CS
|
Citrate Synthase. |
DPH
|
pH difference between inside and outside mitochondria. |
DPSI
|
mitochondrial membrane potential. |
ENOMUT
|
Enolase + Phosphoglycerate Mutase. |
ETC
|
Electron Transport Chain or Respiratory Chain |
FBA
|
Flux Balance Analysis. |
FVA
|
Flux Variability Analysis. |
G1
|
hexokinase + phosphoglucose isomerase. |
G2
|
phosphofructokinase + aldolase + triose-phosphate isomerase. |
G3
|
Glyceraldehyde-3P Dehydrogenase + phosphoglycerate kinase. |
GG3
|
triose phosphate isomerase + aldolase + fructose -1,6-biphosphatase. |
GG4
|
phosphogluco isomerase + glucose-6-phosphatase. |
GLS1
|
Glutaminase. |
GLNUP
|
Uptake of Glutamine. |
GLUCUP
|
Uptake of glucose. |
GLUD1
|
Glutamate Dehydrogenase. |
GOT
|
Glutamate Oxaloacetate Transaminase. |
IDH
|
Aconitase + Isocitrate dehydrogenase. |
L
|
Proton leak of the mitochondrial membrane. |
LACIO
|
Input/Output of lactate. |
LDH
|
Lactate Dehydrogenase. |
MAS
|
Malate/Aspartate Shuttle. |
ME
|
Malic Enzyme. |
MDH
|
Malate Dehydrogenase |
NAGS_ACY
|
N-acetylglutamate synthase + Amino Acylase (ornithine synthesis from glutamate). |
NIG
|
for nigericine, exchange of DPH and DPSI. |
NOS
|
NO synthase. |
NUC
|
Nucleotide (XTP) Synthesis. |
OGC
|
Oxoglutarate carrier (see T2 in Appendix A). |
ORNT1
|
Ornithine/Citrulline + H+ exchanger. |
ORNT2
|
Ornithine/H+ exchanger. |
PDH
|
Pyruvate Dehydrogenase. |
PEPCK
|
PhosphoEnolPyruvate Carboxy Kinase. |
PK
|
Pyruvate Kinase. |
PL1
|
Synthesis of PhosphoLipids. |
PP1
|
Oxidative part of PPP. |
PP2
|
non-oxidative part of PPP. |
PPP
|
Pentose Phosphate Pathway. |
PYC
|
Pyruvate Carboxylase. |
RC1
|
Complex I of Respiratory Chain. |
RC2
|
succinate dehydrogenase + fumarase. |
RC34
|
Complex III+IV of Respiratory Chain. |
SEROUT
|
Output of serine. |
SERSYNT
|
Serine Synthesis = Dehydrogenase + Transaminase and Phosphatase. |
SLP (Substrate Level Phosphorylation)
|
2-oxoglutarate dehydrogenase + succinate thiokinase |
XTP
|
Nucleotides |