Table 1.
Pharmacodynamic index: the neurological function scores, the water content, and area of cerebral infarction. The results were expressed as means ± standard deviation. One-way ANOVA and bilateral inspection were used to analyze the data differences between the groups by some standards that Δ, * p < 0.05; ΔΔ, ** p < 0.01. Δ showed the comparison between the sham operation group, * showed the comparison between the model group.
| Group | Neurological Function Score | The Water Content (%) | Area of Cerebral Infarction (%) |
|---|---|---|---|
| Sham operation group | - | 78.40 ± 0.28 | - |
| Model group | 3.11 ± 0.78 ΔΔ | 82.84 ± 1.08 ΔΔ | 37.95 ± 6.13 ΔΔ |
| Positive group | 1.44 ± 0.53 ** | 79.91 ± 0.64 ** | 14.36 ± 10.20 ** |
| Aloe-emodin | 2.11 ± 1.05 * | 81.03 ± 2.15 ** | 25.09 ± 11.47 ** |
| Emodin | 2.33 ± 1.12 | 80.78 ± 1.52 ** | 20.65 ± 11.51 ** |
| Rhein | 2.22 ± 0.97 * | 81.08 ± 1.21 ** | 24.31 ± 12.19 ** |
| Chrysophanol | 1.89 ± 0.93 ** | 80.10 ± 1.21 ** | 17.16 ± 11.94 ** |
| Physcion | 2.56 ± 1.13 | 81.02 ± 1.64 * | 27.32 ± 10.57 * |
| Aloe-emodin + Emodin | 2.33 ± 0.87 | 81.42 ± 1.45 * | 25.62 ± 12.61 * |
| Aloe-emodin + Rhein | 2.22 ± 0.83 * | 81.52 ± 0.70 * | 25.72 ± 13.21 * |
| Aloe-emodin + Chrysophanol | 2.00 ± 0.71 ** | 80.91 ± 0.91 ** | 27.14 ± 13.14 |
| Aloe-emodin + Physcion | 2.11 ± 0.93 * | 80.52 ± 1.53 ** | 23.56 ± 11.92 * |
| Emodin + Rhein | 2.56 ± 0.88 | 81.65 ± 0.91 * | 27.16 ± 10.25 |
| Emodin + Chrysophanol | 2.44 ± 0.88 | 81.69 ± 1.98 * | 25.91 ± 11.41 * |
| Emodin + Physcion | 2.44 ± 1.13 | 81.34 ± 1.66 ** | 25.57 ± 11.63 * |
| Rhein + Chrysophanol | 2.44 ± 1.01 | 80.38 ± 1.27 ** | 26.66 ± 13.49 * |
| Rhein + Physcion | 2.22 ± 1.21 * | 80.89 ± 1.52 * | 27.70 ± 14.38 |
| Chrysophanol + Physcion | 2.44 ± 0.88 | 81.18 ± 1.11 * | 29.58 ± 15.04 |