Table 2.
Parameter | MM1 | MM2 | MM3 | MM4 | MM5 | MM6 | MM7 | MM8 ** |
---|---|---|---|---|---|---|---|---|
Drug content (%) | 96.05 ± 4.01 | 93.38 ± 2.92 | 99.90 ± 2.62 | 94.47 ± 3.48 | 101.62 ± 2.29 | 102.06 ± 2.47 | 98.25 ± 3.78 | 95.34 ± 4.62 |
pH | 6.33 ± 0.41 | 6.70 ± 0.52 | 6.64 ± 0.43 | 6.85 ± 0.32 | 6.19 ± 0.28 | 6.22 ± 0.44 | 7.04 ± 0.54 | 6.51 ± 0.36 |
Transmittance (%) | 97.22 ± 5.72 | 95.38 ± 5.29 | 97.82 ± 3.83 | 96.17 ± 3.92 | 97.71 ± 3.94 | 95.46 ± 4.42 | 96.43 ± 4.85 | 97.62 ± 3.63 |
Conductivity (mS/cm) | 0.11 ± 0.02 | 0.08 ± 0.01 | 0.20 ± 0.08 | 0.14 ± 0.04 | 0.15 ± 0.07 | 0.16 ± 0.06 | 0.14 ± 0.03 | 0.11 ± 0.03 |
Dilution potential | >10 times | >10 times | >10 times | >10 times | >10 times | >10 times | >10 times | >10 times |
Droplets size (nm) | 41.82 ± 13.71 | 81.04 ± 15.35 | 28.78 ± 10.34 | 47.56 ± 16.28 | 32.41 ± 14.70 | 67.15 ± 15.84 | 47.42 ± 14.11 | 75.99 ± 16.36 |
Polydispersity index | 0.35 ± 0.05 | 0.26 ± 0.03 | 0.38 ± 0.06 | 0.39 ± 0.04 | 0.34 ± 0.02 | 0.30 ± 0.05 | 0.39 ± 0.03 | 0.24 ± 0.02 |
Zeta potential (mV) | −0.33 ± 0.01 | −0.35 ± 0.02 | −0.38 ± 0.012 | −0.28 ± 0.02 | −0.32 ± 0.03 | 0.37 ± 0.03 | −0.29 ± 0.02 | −0.32 ± 0.01 |
Viscosity (cP) | 4.81 ± 1.67 | 6.50 ± 1.17 | 3.28 ± 1.42 | 5.80 ± 1.37 | 4.57 ± 1.47 | 5.86 ± 2.44 | 4.92 ± 1.85 | 6.39 ± 2.24 |
* Mean ± SD (n = 3); ** Check point batch.