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Effects of compound 1 on the expression of IL-6, IL-1β and TNF-α mRNA in LPS-activated macrophages. RAW 264.7 cells were treated for 6 h with compound 1 at indicated concentrations during LPS (1 μg/mL) activation. The mRNA levels of IL-6, IL-1β, and TNF-α were determined by RT-PCR. Veh means vehicle. Images are the representative results of three separate experiments.
