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. 2019 May 15;24(10):1871. doi: 10.3390/molecules24101871

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© 2019 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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The number of osteoclasts per bone perimeter (N.Oc/B.Pm) in each group. (A) Osteoclasts in femur bone tissue of control group rat; (B) osteoclast in femur bone tissue of T1DM group rat; (C) osteoclast in femur bone tissue of T1DM-ICA group rat; (D) the number of osteoclasts per bone perimeter (N.Oc/B.Pm); Values are presented as means ± SD. Different letters indicate statistically significant difference (p < 0.05). Femur bone tissue slides were stained by tartrate resistant acid phosphatase (TRAP), the black arrow points to osteoclasts.