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. 2019 May 14;24(10):1852. doi: 10.3390/molecules24101852

Figure 6.

Figure 6

(a) Diagrammatic illustration of the localization of the binding sites for cisplatin on ODN15 based on the CID fragments of [ODN15 + 2 Pt(NH3)2 − 9H]5− ion observed by MS/MS analysis. Blank box: platinum-free fragments; black-filled box: mono-platinated fragments; red-filled box: di-platinated fragments. * indicates the platination sites deduced by the mono-platinated fragments and * indicates those deduced by the di-platinated fragments. FT-ICR MS observed (top) and theoretical (bottom) isotope pattern of [a8 − G8 + 2Pt(NH3)2 − 3NH3]2− (b) and [w7 + 2Pt(NH3)2 − 2NH3]2− (c).