Table 2.
Release kinetics of gastric phases of f4 peptide fraction from capsules SA-CO, SA-AG, SA-GEm and non-encapsulated peptides.
| Gastric Phase | Time (min) |
Ratio of Released Peptides (mg/L) | ACE Inhibition (%) | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Loaded Capsules of f4 | Non-encapsulated f4 | Loaded Capsules of f4 | Non-encapsulated f4 | ||||||
| SA-CO | SA-AG | SA-GE | SA-CO | SA-AG | SA-GE | ||||
| Oral | 10 | 1.5 | 0.5 | 1.0 | 2.3 | 25.3 | 9.6 | 18.6 | 15.2 |
| Gastric | 120 | 2.1 | 2.7 | 1.6 | 0.8 | 39.5 | 57.4 | 30.3 | 2.7 |
| Duodenal | 120 | 0.3 | 0.6 | 1.4 | 0.1 | 9.5 | 20.4 | 5.0 | 0.0 |
| Total | 250 | 3.9 | 3.8 | 4.0 | 3.8 | 74.3 | 86.4 | 53.9 | 17.9 |