Table 1.

Docking scores (kcal·mol⁻¹) of xanthones 30–40 and positive controls 1–4 onto MDM2 target.

Xanthones 30–40
Ligands	Free Energy of the Ligand: MDM2 (kcal·mol−1)
30	−6.6
31	−6.2
32	−6.6
33	−5.9
34	−6.9
35	−7.2
36	−6.6
37	−7.3
38	−7.1
39	−7.3
40	−7.4
Inhibitors of MDM2-p53 Interaction
Ligands	Free Energy of the Ligand: MDM2 (kcal·mol−1)
1	−7.7
2	−8.0
3	−7.9
4	−8.0