Table A10.

McDonnell 2013, Pathway Covering Using Constant Cost Function.

Pathway	Metabolites Covered
plasmalogen degradation	sn-glycero-3-phosphocholine
purine ribonucleosides degradation to ribose-1-phosphate	guanine, D-ribose 5-phosphate
pyruvate fermentation to (S)-lactate	(S)-lactate, NAD+
stearate biosynthesis	coenzyme A, palmitate, AMP
superpathway of conversion of glucose to acetyl CoA and entry into the TCA cycle	NAD+, glycerone phosphate, coenzyme A, succinate
superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis	(S)-dihydroorotate, orotate, 5-phospho-alpha-d-ribose 1-diphosphate, dTMP
superpathway of pyrimidine ribonucleosides degradation	uridine, uracil, cytidine, 5,6-dihydrouracil