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. 2019 May 2;9(5):88. doi: 10.3390/metabo9050088

Table A13.

McDonnel 2013, Pathway Covering Using Covered Compound Sparseness Cost Function.

Pathway Metabolites Covered
glycerol-3-phosphate shuttle glycerone phosphate, NAD+
guanine and guanosine salvage guanine, 5-phospho-alpha-d-ribose 1-diphosphate
ketolysis coenzyme A, succinate, NAD+
pyruvate fermentation to (S)-lactate (S)-lactate, NAD+
plasmalogen degradation sn-glycero-3-phosphocholine
PRPP biosynthesis D-ribose 5-phosphate, 5-phospho-alpha-d-ribose 1-diphosphate, AMP
pyrimidine deoxyribonucleosides degradation uracil, 2’-deoxycytidine
super pathway of pyrimidine ribonucleosides degradation uridine, uracil, cytidine, 5,6-dihydrouracil
stearate biosynthesis coenzyme A, palmitate, AMP
superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis (S)-dihydroorotate, orotate, 5-phospho-alpha-d-ribose 1-diphosphate, dTMP