Table A4.

ST000061, Pathway Covering Using Covered Compound Sparseness Cost Function.

Pathway	Metabolites Covered
alpha-tocopherol degradation	alpha-tocopherol
anandamide degradation	arachidonic acid, ethanolamine
histamine biosynthesis	L-histidine
L-aspartate biosynthesis	L-aspartate, L-glutamate
L-isoleucine degradation	L-isoleucine, L-glutamate
L-leucine degradation	L-leucine, L-glutamate
L-lysine degradation I (saccharopine pathway)	L-glutamate, L-lysine
L-proline degradation	L-proline, L-glutamate
L-threonine degradation	L-threonine
L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde	L-tryptophan, L-alanine
L-tyrosine biosynthesis	L-phenylalanine, L-tyrosine
L-valine degradation	L-glutamate, L-valine
pregnenolone biosynthesis	cholesterol
purine ribonucleosides degradation to ribose-1-phosphate	guanosine, inosine, hypoxanthine, xanthine
putrescine biosynthesis III	L-ornithine, putrescine
pyrimidine ribonucleosides degradation	uracil
superpathway of conversion of glucose to acetyl CoA and entry into the TCA cycle	2-phospho-d-glycerate, 3-phospho-d-glycerate,
	3-phospho-d-glyceroyl-phosphate, (S)-malate, fumarate,
	citrate, 2,3-diphospho-d-glycerate
triacylglycerol degradation	glycerol