Table A6.

ST000741, Pathway Covering Using Pathway Size Cost Function.

Pathway	Metabolites Covered
anandamide degradation	arachidonic acid
aspirin triggered resolvin D biosynthesis	(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate
CMP-N-acetylneuraminate biosynthesis I (eukaryotes)	N-acetyl-beta-neuraminate
creatine-phosphate biosynthesis	Nomega-phosphocreatine
guanosine nucleotides degradation	urate
myo-inositol biosynthesis	myo-inositol
NAD salvage	nicotinamide
ophthalmate biosynthesis	ophthalmate
plasmalogen degradation	choline, sn-glycero-3-phosphocholine
S-methyl-5’-thioadenosine degradation	S-methyl-5’-thioadenosine
sorbitol degradation I	beta-d-fructofuranose, keto-d-fructose
TCA cycle	(S)-malate, fumarate, cis-aconitate
trehalose degradation	beta-d-glucopyranose, alpha-d-glucopyranose
tRNA-uridine 2-thiolation (mammalian mitochondria)	L-alanine, taurine