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The targets of antimalarial drugs DHA/CQ and V-ATPase inhibitor Baf-A1.
| Drugs | Targets |
|---|---|
| CQ | Accumulation inside the DV; interference with heme; interference with Hz; effect on the membrane integrity; inhibition of lysosomal proteins; interference pH |
| DHA | Activation with ferrous irons; accumulation of ROS; interference the Hb digestion |
| Baf-A1 | Inhibition of V-ATPases; influence on proton pump; inhibition of autophagy; inhibitory activity against bacteria and tumour cell lines etc. |
