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. 2019 May 22;24(10):1977. doi: 10.3390/molecules24101977

Table 3.

CE-LIF based assay advantages and disadvantages.

Advantages Disadvantages
-High sensitivity, high speed
-High reproducibility
-Small number of samples required
-Minimal preparation time
-Easy automation, high throughput for profiling of complex biological samples
-Possible on-column concentration
-Highly efficient multidimensional separation
-Derivatization required
-Instability of the laser power
-Excitation range is limited
-No standardized method