Figure 3.

Non-newly generated immature neurons (nng-INs) in the cerebral cortex. (A) Cortical nng-INs are detectable by doublecortin (DCX) staining in layer II; in rodents, they are restricted to the paleocortex (right); arrowhead: Limit between paleo- and neo-cortex. (B) They occur in two different morphological types: Type 1 (small, bipolar) and type 2 cells (large, multipolar); (C) the nngIN cell types show different degree of immaturity: Type 1 cells are more immature than type 2 cells, as revealed by a different combination of markers. Modified from: (A) [71,108]; (C) [35].