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. 2019 Feb 27;151(6):786–797. doi: 10.1085/jgp.201812236

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© 2019 Morales et al.

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Figure 9. — L-type channel inactivation processes upon β-adrenergic stimulus. Representative nifedipine-sensitive current (solid line) elicited by the AP (dashed line) prerecorded from the same cell in a newborn rat cardiomyocyte overexpressing RFP (A), Ca_Vβ_2a (B), CaM_wt (D), or CaM₃₄ (E). Bar graphs are mean ± SEM (n = 8) of maximal current normalized by cell capacitance (pA/pF), total time of current normalized by action potential duration (TTC_norm), and the total current integral normalized by cell capacitance (Q_total) from a cardiomyocyte overexpressing RFP (empty bars) and Ca_Vβ_2a (plum bars). CaM_wt (empty bars; B) or CaM₃₄ (blue bars; D). Data are presented as percentages of their respective control situation [RFP for C and CaM_wt for F]. *, P < 0.01 with respect to control.