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. 2019 May 2;151(6):834–849. doi: 10.1085/jgp.201812143

Table 1. VIP and CCh modulate CFTR distribution and confined mobility at the cell surface of pHBE cells through lipid-dependent mechanisms.

Treatment CD ratio DA ratio Dmicro (µm2/s) × 0.001 fmicro R (μm) ncella Nexpb
Ctr 1.0 ± 0.1 1.0 ± 0.1 10.9 ± 0.6 0.21 ± 0.02 0.322 ± 0.005 224 10
VIP 0.50 ± 0.05c 2.7 ± 0.4d 3.3 ± 0.2c 0.40 ± 0.03d 0.279 ± 0.005c 164 8
CCh 0.38 ± 0.08c 2.5 ± 0.3d 4.77 ± 0.6c 0.35 ± 0.04d 0.283 ± 0.004c 40 2
COase +VIP 0.87 ± 0.08 1.0 ± 0.1 10.7 ± 0.7 0.18 ± 0.02 0.303 ± 0.005 112 4
Ami +VIP 1.4 ± 0.2d 0.50 ± 0.07c 18.0 ± 1.0d 0.14 ± 0.01c 0.335 ± 0.005 85 4
a

(ncell) total number of cells

b

(Nexp) number of independent experiments

c

Smaller than Ctr, pcell < 0.001, pexp < 0.05.

d

Larger than Ctr, pcell < 0.001, pexp < 0.05