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. 2019 Apr 28;8(5):587. doi: 10.3390/jcm8050587

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© 2019 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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(A) Kaplan-Meier curves for rejection-free survival of slow (red lines) and fast metabolizers (blue lines), analyzed by the Kaplan–Meier method and compared using the log-rank test. Fast metabolizers showed a noticeably reduced rejection-free survival. (B) Subtype analysis of the first rejection episode within the first five years after transplantation. Fast metabolizers experienced increased frequencies of humoral and mixed acute rejection, whereas slow metabolizers were mainly affected by borderline rejections.