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Structural overview of hLPYK. Model of hLPYK (PDB entry 4ip7). Each monomer of the homotetramer is composed of three domains (A, B and C). The B domain interacts with the A domain of the same subunit. The A–A interface is formed between A domains from adjacent monomers. The C–C interface is formed by adjacent C domains. The allosteric sites are positioned along the C–C interface (shown in green for one monomer).
