Table 1.
Biosample | Relative Contents (%) | ||||||||
---|---|---|---|---|---|---|---|---|---|
Phase I Reaction | Phase II Reaction | Phase I Metabolites | |||||||
-CH3 | +2H | +OH | +SO3 | +GlcUA | +Vc | +Glc | +CH3 | ||
urine | 55.14 | 37.01 | 57.79 | 74.60 | 25.83 | 1.08 | 0.23 | 3.93 | 1.78 |
feces | 71.51 | 44.43 | 21.55 | 73.53 | 1.62 | 15.54 | — | — 1 | 9.30 |
plasma | 36.58 | 25.72 | 22.78 | 36.17 | 67.87 | 0.44 | — | 3.16 | — |
colon | 57.95 | 58.48 | 28.30 | 55.81 | 16.61 | 9.23 | — | 0.78 | 17.57 |
intestine | 39.56 | 41.46 | 36.17 | 15.62 | 78.04 | 7.60 | — | 11.23 | 0.99 |
stomach | 39.46 | 22.38 | 26.67 | 35.00 | 54.57 | 1.23 | — | 2.50 | 9.20 |
liver | 62.62 | 31.43 | 13.33 | 57.11 | 42.09 | — | — | 3.55 | 0.80 |
spleen | 33.84 | 23.45 | 8.74 | 27.79 | 71.33 | — | — | 1.03 | 0.88 |
kidney | 60.90 | 30.46 | 34.93 | 63.43 | 36.30 | 0.10 | — | 1.67 | 0.17 |
lung | 34.25 | 22.91 | 5.29 | 28.22 | 71.78 | — | — | — | — |
heart | 33.74 | 22.74 | 6.19 | 27.76 | 71.70 | — | — | — | 0.54 |
brain | 57.11 | 20.86 | — | 57.11 | 42.89 | — | — | — | — |
thymus | 25.25 | 15.66 | 9.12 | 18.96 | 80.54 | — | — | 2.01 | 0.49 |
1 —, undetected.