Figure 2.

Histological findings showing stages of tubular regression in testicular tissues of transgender patients. Representative periodic acid-Schiff stained seminiferous tubules. (A) Tubule with complete spermatogenesis contains different types of germ cells. Spermatogonia (arrowhead), spermatocytes (black arrow) and elongated spermatids (white arrow). (B) In meiotic arrest spermatogonia (arrowhead) and spermatocytes (black arrow) are present. (C) Spermatogonial arrest shows only spermatogonia (arrowhead). (D) Sertoli cell only phenotype without germ cells. (E) Tubular shadow without any cells in the lumen. Tubular regression is described from A–E.