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. 2019 May 11;11(5):229. doi: 10.3390/pharmaceutics11050229

Figure 5.

Figure 5

Blocking of norovirus (NoV) VLP binding to histo-blood group antigens (HBGAs). Two-fold diluted, group-wise pooled sera of mice immunized with 0.3 µg NoV GI.4 and GII.4-2006a VLPs alone, or mixed with 10 µg VP6, and the control (Ctrl) mice sera were tested for potential to block binding of NoV (A) GI.4 or (B) GII.4-2006a VLPs to HBGAs present in pig gastric mucin (PGM). Shown are group mean blocking index (%) with standard error of the mean. Horizontal dashed line represents 50% blocking.