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. 2019 May 12;9(5):97. doi: 10.3390/metabo9050097

Table 1.

Changes in the levels of sesquiterpene lactones in Lactuca sativa.

No. Compound Rol ABC (RA) Rol C (RC) Commercial (COM)
↑/↓ % Change ± SEM p Value ↑/↓ % Change ± SEM p Value ↑/↓ % Change ± SEM P Value
1 Lactucopicrin 17 ± 10.3 0.272 85 ± 31.6 0.048 * 90 ± 8.9 0.009 **
2 Lactucopicrin-15-oxalate 79 ± 14.1 0.020 * 29 ± 18.3 0.183 6 ± 0.5 0.403
3 11β,13-dihydrolactucopicrin 132 ± 6.3 0.002 ** 257 ± 4.4 0.006 ** 127 ± 4.9 0.003 **
4 Lactucin - Unchanged N/A unchanged N/A 667 ± 145.3 0.005 **
5 Lactucin-sulfate 25 ± 5.6 0.177 95 ± 26.7 0.027 * 90 ± 11.1 0.009 **
6 15-deoxylactucin-8-sulfate 93 ± 3.1 0.008 ** 95 ± 1.5 0.007 ** 56 ± 1.0 0.035 *
7 15-deoxylactucin-8-sulfate-Gln 535 ± 98.9 0.005 ** 511 ± 68.8 0.001 ** 89 ± 5.3 0.009 *
8 15-deoxylactucin-8-sulfate-Pro 96 ± 1.4 0.007 ** 97 ± 0.4 0.007 ** 50 ± 1.8 0.048 **
9 15-deoxylactucin-8-sulfate-Val 1103 ± 99.1 0.061 1028 ±164.9 0.002 ** 20 ± 3.1 0.214
10 8-deacetylmatricarin-8-sulfate 28 ± 15.8 0.182 128 ± 43.8 0.030 * 207 ± 13.1 0.001 **
11 Cichorioside B-sulfate 83 ± 10.3 0.014 * 149 ± 26.9 0.006 * 52 ± 8.6 0.047 *
12 1-β-(4-hydroxyphenylacetyl)-15-O-β-d-glucopyranosyl-5α, 6βH-eudesma-3-en-12, 6α-olide 327 ± 48.2 0.029 * 29 ± 23.6 0.220 100 ± 9.8 0.007 **

Table shows the percentage change in levels of sesquiterpene lactones compared with untransformed (unT) Lactuca sativa plants. Values are % mean (± SEM) and P values indicate differences with unT plants (* p < 0.05, ** p < 0.01).