Table 3.
Donors | Control Group (n = 85) | RIPC Group (n = 85) | p-Value |
Progression to chronic kidney disease, n (%) | 6 (7.1) | 8 (9.4) | 0.78 |
Proportion with sCr ≥ 1.4 mg/dL at discharge, n (%) | 17 (20.0) | 6 (7.1) | <0.05 |
Recipients | Control Group (n = 83) | Treated Group (n = 85) | p-Value |
Time to 50% decrease in sCr, days | 1.1 ± 0.6 | 1.4 ± 3.2 | 0.58 |
Delayed graft function, n (%) | 0 (0.0) | 2 (2.4) | 0.49 |
Acute rejection, n (%) | 5 (6.0) | 5 (5.9) | 1.00 |
Graft failure, n (%) | 1 (1.2) | 0 (0.0) | 0.99 |
eGFR at discharge, mL/min/1.73 m2 | 87.9 ± 17.7 | 83.9 ± 19.4 | 0.18 |
Mean difference 1 | −3.23 (−8.62–2.16) | 0.14 | |
eGFR at postoperative 1 year, mL/min/1.73 m2 | 77.0 ± 24.5 | 79.5 ± 18.2 | 0.49 |
Mean difference 1 | 3.45 (−3.11–10.01) | 0.29 |
RIPC, remote ischemic preconditioning; sCr, serum creatinine; eGFR, estimated glomerular filtration rate. eGFR was calculated using the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equation. 1 Difference in means (95% CI) adjusted for warm ischemic time and preoperative serum creatinine, age and baseline eGFR of donor.