Table 4.
Multiple linear regression analysis of lung function according to CT-measured skeletal muscle index (SMICT) quartiles.
| Variable | Q1 | Q2 | Q3 | Q4 | p for Trend |
|---|---|---|---|---|---|
| Male | |||||
| FVC, liters | |||||
| Model 1 | Reference | 0.18 (0.10, 0.26) | 0.29 (0.21, 0.38) | 0.40 (0.31, 0.49) | <0.001 |
| Model 2 | Reference | 0.18 (0.10, 0.26) | 0.28 (0.20, 0.37) | 0.39 (0.30, 0.48) | <0.001 |
| Model 3 | Reference | 0.09 (0.01, 0.16) | 0.14 (0.06, 0.21) | 0.18 (0.10, 0.26) | <0.001 |
| FEV1, liters | |||||
| Model 1 | Reference | 0.11 (0.04, 0.18) | 0.19 (0.12, 0.25) | 0.28 (0.20, 0.35) | <0.001 |
| Model 2 | Reference | 0.10 (0.04, 0.17) | 0.18 (0.11, 0.25) | 0.28 (0.20, 0.35) | <0.001 |
| Model 3 | Reference | 0.04 (−0.02, 0.10) | 0.08 (0.01, 0.14) | 0.12 (0.05, 0.19) | 0.007 |
| Female | |||||
| FVC, liters | |||||
| Model 1 | Reference | 0.10 (−0.00, 0.20) | 0.17 (0.07, 0.27) | 0.23 (0.12, 0.34) | 0.001 |
| Model 2 | Reference | 0.09 (−0.01, 0.19) | 0.17 (0.06, 0.27) | 0.23 (0.11, 0.34) | 0.001 |
| Model 3 | Reference | 0.08 (−0.01, 0.17) | 0.12 (0.02, 0.21) | 0.14 (0.03, 0.24) | 0.047 |
| FEV1, liters | |||||
| Model 1 | Reference | 0.05 (−0.03, 0.13) | 0.10 (0.02, 0.19) | 0.18 (0.09, 0.27) | 0.001 |
| Model 2 | Reference | 0.04 (−0.04, 0.13) | 0.11 (0.02, 0.19) | 0.19 (0.09, 0.28) | 0.001 |
| Model 3 | Reference | 0.03 (−0.05, 0.11) | 0.07 (−0.01, 0.15) | 0.12 (0.03, 0.21) | 0.056 |
β regression coefficient (95% confidence interval). 1 Adjusted for age and body mass index (BMI). 2 Adjusted for age, BMI, smoking, and exercise. 3 Adjusted for age, BMI, smoking, exercise, systolic blood pressure (BP), diastolic BP, height, total cholesterol, triglyceride, high-density lipoprotein (HDL) cholesterol and hemoglobin A1c. Cutoff values of SMICT quartiles (cm2/(kg/m2)) for males, 8.53, 9.29, 10.15; and for females, 7.26, 7.94, 8.94.