Figure 5.

Histological analysis of the soleus (SOL) in non-dystrophic and mdx mice. Fiber size distribution in non-dystrophic (A) and mdx (B) animals treated with low (white bar), medium (orange bar) and high (black bar) vitamin D enriched diets. Representative images are depicted in panel (C); low, medium and high vitamin D diets (C57 i–iii and mdx iv–vi, respectively). Fibre cross-sectional area (CSA; (D)), percentage of regeneration (mdx only; (E)) and damage (F) was also analysed in non-dystrophic C57 and mdx mice fed low, medium and high amounts of vitamin D. Symbols indicate: ^^^^ p < 0.0001, significantly different to C57 strain. All groups n = 4. Scale bar = 50 μm.