Table 3.
Multivariate-adjusted hazard ratios 1 for all-cause mortality of serum EPA, DHA, and ARA (n = 1054).
| Explanatory Variable | Tertile 1 | Tertile 2 | Tertile 3 | p trend | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Median | Cases n /Alive n | HR (ref) | Median | Cases n /Alive n | HR (95% CI) |
Median | Cases n /Alive n | HR (95% CI) |
|||||
| Serum EPA | 38.1 | μg/mL | 150/200 | 1 | 62.9 | μg/mL | 133/218 | 0.82 (0.61–1.10) |
101.9 | μg/mL | 139/214 | 0.81 (0.60–1.09) |
0.17 |
| Serum DHA | 111.6 | μg/mL | 151/197 | 1 | 147.1 | μg/mL | 143/210 | 0.82 (0.61–1.10) |
191.0 | μg/mL | 128/225 | 0.73 (0.53–0.99) |
0.047 |
| Serum ARA | 116.7 | μg/mL | 136/213 | 1 | 144.0 | μg/mL | 156/195 | 1.47 (1.10–1.98) |
184.2 | μg/mL | 130/224 | 0.90 (0.64–1.24) |
0.51 |
| Serum EPA/ARA | 0.3 | 141/212 | 1 | 0.4 | 128/223 | 0.62 (0.45–0.84) |
0.7 | 141/212 | 0.71 (0.53–0.96) |
0.02 | |||
1 HR adjusted for sex, baseline age, body mass index, smoking status, alcohol drinking, physical activity, education, employment, and history of cancer, heart disease, stroke, hypertension, dyslipidemia, and diabetes mellitus. HR, hazard ratios; CI, confidence intervals; EPA, eicosapentaenoic acid; DHA, docosahexaenoic acid; ARA, arachidonic acid.